Yazar "Çıkrıkçı, Kübra" için listeleme
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Determination of paraoxonase 1 activity and phenotype distribution in cervical disk herniation patients
Adilay, Utku; Katar, Salim; Çıkrıkçı, Kübra; Gencer, Nahit (Balıkesir Üniversitesi, 2024)Determination of Paraoxonase 1 Activity and Phenotype Distribution in Cervical Disk Herniation Patients Abstract Objectives: Cervical disk herniation (CDH) is a common disease that usually develops as a result of intervertebral ... -
The effects of cardiac drugs on human erythrocyte carbonic anhydrase I and II isozymes
Argan, Onur; Çıkrıkçı, Kübra; Baltacı, Aybike; Gencer, Nahit (Taylor and Francis Ltd, 2020)Cardiovascular diseases are the leading cause of mortality worldwide. In recent years, the relationship between carbonic anhydrase inhibitors and atherosclerosis has attracted attention. In this study, we aimed to determine ... -
Evaluation of carbonic anhydrase and paraoxonase inhibition activities and molecular docking studies of highly water-soluble sulfonated phthalocyanines
Güzel, Emre; Sönmez, Fatih; Erkan, Sultan; Çıkrıkçı, Kübra; Ergun, Adem; Gencer, Nahit; Arslan, Oktay; Koçak, Makbule Burkut (Scientific Technical Research Council Turkey-Tubitak, 2020)The investigation of carbonic anhydrase and paraoxonase enzyme inhibition properties of water-soluble zinc and gallium phthalocyanine complexes (1 and 2) are reported for the first time. The binding of p-sulfonylphenoxy ... -
Investigation of the effects of some pesticides on carbonic anhydrase isoenzymes
Baltacı, Aybike; Çıkrıkçı, Kübra; Gençer, Nahit (Wiley, 2023)The aim of this study was to investigate the inhibitory effects of some pesticides known to have harmful effects on human health on carbonic anhydrase isoenzymes. Therefore, carbonic anhydrase isoenzymes (hCA I and II) ... -
Single-step purification of catalase enzyme from human blood erythrocytes using affinity chromatography technique
Çıkrıkçı, Kübra; Gencer, Nahit (Hindawi, 2024)In this study, we aimed to isolate and purify catalase from human blood erythrocytes by using a newly synthesized affinity gel. The synthesized ω-amino hexyl agarose-1,2,3-triazole-5-carboxylic acid affinity gel was analyzed ... -
Synthesis, characterization, carbonic anhydrase inhibitor activity, and docking studies of phenylthiazol-2(3h)-ylidene-isoquinoline-5-amine derivatives
Berber, Nurcan; Şahutoğlu, Arif Sercan; Gökçe, Başak; Çıkrıkçı, Kübra; Gençer, Nahit (Elsevier, 2023)Phenylthiazol-2(3h)-ylidene-isoquinoline-5-amine derivatives(5a-r) were easily prepared from 5-aminoisoquinoline, thioisocyanate, and phenacyl bromide derivatives in the presence of triethylamine in tetrahydrofuran (THF), ... -
Sıvı kardiyak ilaçların karbonik anhidraz I ve II izoenzimleri üzerindeki etkileri
Argan, Onur; Çıkrıkçı, Kübra; Gencer, Nahit (Balıkesir Üniversitesi, 2022)Kardiyovasküler hastalıklar dünya çapında ölümlerin önde gelen nedenidir. Son yıllarda karbonik anhidraz inhibitörleri ile ateroskleroz arasındaki ilişki dikkat çekmektedir. Bu çalışmada, sık kullanılan sıvı kardiyak ...
